David Mills

David Mills

David Mills, Ph.D.

Position Title
Peter J. Shields Chair in Dairy Food Science

Food Science and Technology

3142 Robert Mondavi Institute - North

David Mills is a Professor in the Departments of Viticulture & Enology and Food Science & Technology at the University of California at Davis. Dr. Mills has over 20 years experience working on the molecular biology of Gram-positive microorganisms, with an emphasis on the lactic acid bacteria (LAB) and bifidobacteria used in food fermentations or active as probiotics. An overall goal of Dr. Mills research is to link genomic content, ecological context and specific strain behavior to better understand LAB biology in their “working” environments. Dr. Mills is the founder of the LAB Genomics Consortium and is a founding member of the UC Davis Milk Bioactives and Functional Glycobiology Programs. Dr. Mills is a past Chair of the Food Microbiology Division for the American Society for Microbiology where he has also served as a Waksman Foundation Lecturer. Dr. Mills currently serves as an associate editor for the journal Microbiology. In 2010 Dr. Mills was awarded the Cargill Flavor Systems Award from the American Dairy Science Association. In 2012 Dr. Mills became the Peter J. Shields Endowed Chair in Dairy Food Science at UC Davis.

Selected Publications

Bokulich, N, and D. A. Mills. 2012. Next-generation approaches to the microbial ecology of food fermentations. Journal of Biochemistry and Molecular Biology (In Press).

Garrido, D., C. Nwosu, S. Ruiz-Moyano, D. Aldredge, J. B. German, C. B. Lebrilla and D. A. Mills. 2012. Endo-beta-N-acetylglucosaminidases from infant-gut associated bifidobacteria release complex N-glycans from human milk glycoproteins. Molecular and Cellular Proteomics (In Press).

Chichlowski, M., G. De Lartigue, J. B. German, H. E. Raybould and D. A. Mills. 2012. Select bifidobacteria cultured on human milk oligosaccharides affect intestinal epithelial function. Journal of Pediatric Gastroenterology and Nutrition (In Press).

Bokulich, N. A., C. M. Lucy, G. Allen, A. K. Benson and D. A. Mills. 2012. Next-generation sequencing reveals significant bacterial diversity of botrytized wine. PLoS One 7:e36357.

Bokulich, N. A., C. Bamforth, and D. A. Mills. 2012. Brewhouse-resident microbiota responsible for fermentation of American coolship ale. PLoS One 7:e35507.

Chichlowski, M., J. B. German, C. B. Lebrilla and D. A. Mills. 2011. The influence of milk oligosaccharides on the microbiota of infants: Opportunities for formulas. Annual Reviews in Food Science and Technology 3:331-351.

Sela, D. A., Y. Li, L. Lerno, S. Wu, A. M. Marcobal, J. B. German, Xi Chen, C. B. Lebrilla and D. A. Mills. 2011. An infant-associated bacterial commensal utilizes breast milk sialyoligosaccharides. Journal of Biological Chemistry 286:11909-11918.

Zivkovic, A., J. B. German, C. B. Lebrilla and D. A. Mills. 2011. The human milk glycobiome and its impact on the infant gastrointestinal microbiota. Proceedings of the National Academy of Sciences 108:4653-4658.

Garrido, D., J.-H. Kim, J. B. German, H. E. Raybould, and D. A. Mills. 2011. Oligosaccharide binding proteins from Bifidobacterium longum subsp. infantis reveal a preference for host glycans. PLoS ONE 6:e175315.

Sela. D. A. and D. A. Mills. 2010. Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides. Trends in Microbiology 18:298-307.

Marcobal, A., M. Barboza, J. Froehlich, D. E. Block, J. B. German, C. B. Lebrilla and D. A. Mills. 2010. Consumption of human milk oligosaccahrides by gut-related microbes. Journal of Agricultural and Food Chemistry 58:5334-40.

LoCascio, R. G., M. R. Ninoneuvo, S. R. Kronewitter, S. F. Freeman, J. B. German, C. B. Lebrilla, and D. A. Mills. 2009. A versatile and scalable strategy for glycoprofiling bifidobacterial consumption of human milk oligosaccharides. Microbial Biotechnology 2:333-342.

Sela, D. A., J. Chapman, A. Adeuya, T.R. Whitehead, A. Lapidus, D.S. Rokhsar, C.B. Lebrilla, J.B German, N.P. Price, P.M. Richardson, and D.A. Mills. 2008. The complete genome sequence of Bifidobacterium longum subsp. infantis suggests adaptation for milk utilization within the infant microbiome. Proceedings of the National Academy of Sciences 105:18964-18969.

Makarova, K.,.—51 authors—B. Weimer, and D. A. Mills. 2006. Comparative genomics of the lactic acid bacteria. Proceedings of the National Academy of Sciences 103:15611-15616.