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David M. Ogrydziak
Professor and Food Microbiologist
Degree
Ph. D. Massachusetts Institute of Technology, 1975
Research
Professor Ogrydziak is researching protein secretion and protein processing and response to secretion stress in the yeast Yarrowia lipolytica. He is also working with genetic manipulations of microorganisms as sources of enzymes or other fermentation products useful in food processing. His research is also exploring the heterologous protein production by Yarrowia lipolytica and conducting analysis of genome sequence of Yarrowia lipolytica.
Selected Publications
Matoba, S., J. Fukayama, R.A. Wing and D.M. Ogrydziak. 1988. Intracellular precursors and secretion of the alkaline extracellular protease of Yarrowia lipolytica. Molecular Cellular Biology 8:4904-4916.
Yaver, D.S., S. Matoba and D.M. Ogrydziak. 1992. A mutation in the signal recognition particle 7S RNA of the yeast Yarrowia lipolytica preferentially affects synthesis of the alkaline extracellular protease: In vivo evidence for translational arrest. Journal of Cellular Biology 116:605-616.
Fournier, P., A. Abbas, M. Chasles, B. Kudla, D.M. Ogrydziak, D. Yaver, J. Xuan, A. Peito, A. Ribet, C. Feynerol, F. He and C. Gaillardin. 1993. Colocalization of centromeric and replicative functions on autonomously replicating sequences isolated from the yeast Yarrowia lipolytica. Proceedings of the National Academy of Science USA 90:4912-4916.
Lee, I.H. and D.M. Ogrydziak. 1997. Yarrowia lipolytica SRP54 homolog and translocation of Kar2p. Yeast 13:499-513.
Kim, K. and D.M. Ogrydziak. 2000. Yarrowia lipolytica SRP receptor a-subunit. Yeast 16:1243-1252.