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Chester W. Price
Professor and Food Microbiologist
Degree
Ph. D. University of California at Davis, 1976
Research
Dr. Price researches bacterial stress responses, molecular genetics, genomics, bioinformatics and food safety. The general stress response contributes to bacterial survival in the environment, in foods and in pathogenic interactions. He is studying this response using Bacillus subtilis as a model for related food-borne pathogens such as Listeria monocytogenes and Staphylococcus aureus. Among these organisms, the response is controlled by the Sigma-B transcription factor, and loss of Sigma-B function causes multiple stress sensitivity and decreased virulence.
Selected Publications
Vijay, K., M.S. Brody, E. Fredlund and C.W. Price. 2000. A PP2C phosphatase containing a PAS domain is required to convey signals of energy stress to the sigma-B transcription factor of Bacillus subtilis. Molecular Microbiology 35:180-188.
- Price, C.W., P. Fawcett, H. Cérémonie, N. Su, C.K. Murphy and P. Youngman. 2001. Genome-wide analysis of the general stress response in Bacillus subtilis. Molecular Microbiology 41:757-774.
Price, C.W. 2002. General stress response. p. 369-384, IN: Sonenshein, A.L., R. Losick, and J.A. Hoch (eds.), Bacillus subtilis and Its Closest Relatives: from Genes to Cells. American Society for Microbiology, Washington, D.C.
Kim, T.J., T.A. Gaidenko and C.W. Price. 2004. A multicomponent protein complex mediates environmental stress signaling in Bacillus subtilis. Journal of Molecular Biology 341:135-150.
- Hua, L., P.S. Hefty, Y.J. Lee, Y.M. Lee, R.S. Stephens and C.W. Price. 2006. Core of the partner switching mechanism is conserved in the obligate intracellular pathogen Chlamydia trachomatis. Molecular Microbiology 59:623-636.
Awards and Honors
- Foundation Lecturer, American Society for Microbiology, 1991-1992
Extension of Knowledge Activities
For more information on Dr. Price, visit his home page.